| Song Title | Artist | Genre |
|---|---|---|
| Sending This One Out | Loco Dice f./Just Blaze | Powerset 6 |
| Senor Sereno | Edwin Lebron | Salsa |
| Senora | Vena | Bachata |
| Senorita | Reykon f./Daddy Yankee | Reggaeton |
| Senorita (Take A Shot) | Treal Lee f./Prince Rick | Rhythm/Urban |
| Sensei | Flip | |
| Sensual Smooth | BMV | |
| Sentimiento | Vico C f./Arcangel | Throwback |
| Separator | Crystal Fighters | Rock |
| September | Daughtry | Top 40 |
